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In principle, yes, but tricky...
have a look here:
https://www.kickstarter.com/projects/1602548140/jevois-open-source-quad-core-smart-machine-vision/posts/1786008
there is a small dot of glue on the thread which makes it hard to unscrew.
Another option is to get a different OV9653 sensor with a different lens, just make sure it has the same 24-pin, 0.5mm pitch flat flex cable. Check this post out:
http://jevois.org/qa/index.php?qa=153